Interactions between Cialis Oral and sildenafil-edtadalafil-hiv-protease-inhibitorscobicistat



Interactions.
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
Your protease inhibitor may slow down how quickly your liver processes sildenafil and tadalafil.
Your blood levels of sildenafil or tadalafil may increase and cause harmful effects.
Let your healthcare professional (e.g. doctor or pharmacist) know that you are taking these medicines together. If you are taking sildenafil for pulmonary arterial hypertension (PAH), contact your doctor right away. Contact your doctor if you experience a painful or prolonged erection, fainting or dizziness, or changes in vision. The dose of your sildenafil or tadalafil may need adjusting.Your healthcare professionals (e.g. doctor or pharmacist) may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
1.Viagra (sildenafil) US prescribing information. Pfizer Inc. September, 2015.
2.Reyataz (atazanavir sulfate) US prescribing information. Bristol-Myers Squibb Company May, 2017.
3.Prezista (darunavir) US prescribing information. Tibotec Inc. June 19, 2017.
4.Lexiva (fosamprenavir calcium) US prescribing information. GlaxoSmithKline September, 2016.
5.Crixivan (indinavir sulfate) US prescribing information. Merck & Co., Inc. September, 2016.
6.Kaletra (lopinavir/ritonavir tablets) US prescribing information. Abbott Laboratories June 15, 2017.
7.Viracept (nelfinavir mesylate) US prescribing information. Agouron Pharmaceuticals, Inc. September, 2016.
8.Norvir (ritonavir) US prescribing information. Abbott Laboratories June 29, 2017.
9.Invirase (saquinavir mesylate) US prescribing information. Roche Laboratories, Inc. September, 2016.
10.Aptivus (tipranavir) US prescribing information. Boehringer Ingelheim Pharmaceuticals, Inc. September, 2016.
11.Revatio (sildenafil citrate) US prescribing information. Pfizer Inc. April, 2015.
12.Cialis (tadalafil) US prescribing information. Eli Lilly and Company April, 2016.
13.Back DJ. Re: ‘Pharmacokinetic interactions between sildenafil and saquinavir/ritonavir’. Br J Clin Pharmacol 2000 Aug;50(2):85.
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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
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